![Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females | Life Science Alliance Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females | Life Science Alliance](https://www.life-science-alliance.org/content/lsa/2/4/e201900386/F2.large.jpg)
Heterozygous loss of function of IQSEC2/Iqsec2 leads to increased activated Arf6 and severe neurocognitive seizure phenotype in females | Life Science Alliance
![Ca2+-induced release of IQSEC2/BRAG1 autoinhibition under physiological and pathological conditions | Journal of Cell Biology | Rockefeller University Press Ca2+-induced release of IQSEC2/BRAG1 autoinhibition under physiological and pathological conditions | Journal of Cell Biology | Rockefeller University Press](https://cdn.rupress.org/rup/content_public/journal/jcb/222/12/10.1083_jcb.202307117/1/m_jcb_202307117_fig4.png?Expires=1702115998&Signature=4ZDMXqM8uEFBQTIBQ6nsevOJlMvVQl5MuQv4AbX5-7B-IGmiJnt9w5TFSNhmfEchXVMUqlB6F1ESDPzuO180MVSFdY7q-BGJ6bVwBsGVu823undnDNMVj8xgH7C1i74PUF2~o3cq8YuPBltyxBU-nQ5N-Md3yTGEMtELy0XuPzlFTIMlSwFRii4VZb0ORuVdI6gvNOCdLXCDPBMoAb63iHDMwL9aRGSZRxuy~dmuM-xEigIBQGNxGu54KI~lyL6h~0DdFj4GIZM84jDQ~ipmk9qWUd4K~AZaCxrsmc8ZGmMXVan2gfFKnMB4CPrJ6YNMm2~GWUANcYmFeJ7XJK0n2g__&Key-Pair-Id=APKAIE5G5CRDK6RD3PGA)
Ca2+-induced release of IQSEC2/BRAG1 autoinhibition under physiological and pathological conditions | Journal of Cell Biology | Rockefeller University Press
![Deep phenotyping of 14 new patients with IQSEC2 variants, including monozygotic twins of discordant phenotype - Radley - 2019 - Clinical Genetics - Wiley Online Library Deep phenotyping of 14 new patients with IQSEC2 variants, including monozygotic twins of discordant phenotype - Radley - 2019 - Clinical Genetics - Wiley Online Library](https://onlinelibrary.wiley.com/cms/asset/cf6d1bb3-3387-4a7e-b595-d130882e57e4/cge13507-fig-0001-m.jpg)
Deep phenotyping of 14 new patients with IQSEC2 variants, including monozygotic twins of discordant phenotype - Radley - 2019 - Clinical Genetics - Wiley Online Library
![Precision medicine for the rescue of specific impairments in social behavior associated with the A350V Iqsec2 mutation | bioRxiv Precision medicine for the rescue of specific impairments in social behavior associated with the A350V Iqsec2 mutation | bioRxiv](https://www.biorxiv.org/content/biorxiv/early/2020/11/05/2020.11.04.368282/F2.large.jpg)